Healing Sports Injury with Stem Cell therapy

Sports injuries are quite common issue in professional sports or basic sports because, indulgence into strenuous activities, increase usual wear and tear of the tissues and may require immediate medical attention. As our joints and hinges are backed by the muscles, ligaments, tendons and cartilages to provide them the support, strength and ease of locomotion that are highly in demand in a life of an athlete or sports person. However, overuse, sudden trauma or injuries can put them into a lifetime dependency and end of their career.

Sports injury may vary exactly as different sports genres are. Some of the injuries can be so devastating that they stay for long and can make a person permanently disable. While some injuries can be managed with effective physiotherapy along with some effective scientific advancement such as “stem cells therapy”. Stem cells are the repairing cells of damaged tissues, which are operative by harnessing the healing power of body. Apparently, Stem Cells Therapy can be considered as an effective, alternative therapy. Stem cells isolation can be done effectively and quickly from different mature adult sources, such as bone marrow or adipose tissue (fat cells), and injecting it into the damaged body part to promote healing.

In case of sports injuries, these stem cells are identifying to be displaying different types of differentiation capacity, such as bone cells, cartilaginous cells, etc. It has been as well studies so far that autologous platelet rich plasma, if utilized to stimulated patients own stem cells, the secreted growth factors can redirect these stem cells at the site of injury and force them to differentiate into desired cells types.

Some of the injuries that can be greatly helped by stem cells are:

•    Achilles Tendon Injury: - The Achilles tendons, is one of the longest tendons in our body, extending from the calf muscles to the bones of heels. It allows us to extend our feet and point our toes to the floor. The injury is associated with the swollen or broken tendon.

•    Knee Ligament Injuries: - Anterior cruciate ligament, Posterior Crucial Ligament, lateral ligament and medial ligaments are the four very crucial ligaments of the skin and can be injured due to sudden twisting, jumping, landing etc. The injury can be very painful with permanently debilitating changes.

•    Ankle Injuries: - They can be sprains, strains or fractures associated with tearing or breakage of bone, tendons or ligaments.

•    Concussions:- These are the most common traumatic brain injuries, associated with direct low or bump to the head. The brain is made up of soft tissue, cushioned by spinal fluid and encased in the protective shell of the skull. When a sudden concussion is sustained, the impact can jolt our brain; leading to bruising, blood vessel damage, nerves injuries or damage.

•    Dislocation: - This is a kind of injury, wherein the fall or blow causes the bone to pop out of its socket, especially in the case of joints. In severe cases, the tissue and nerves around get damaged leading to the loss of mobility.

•    Golfer's Elbow: - Golfer's elbow cause pain and inflammation in the tendons that connect the forearm to the elbow.

•    Groin Pull: - They are common in people who require a lot of running and jumping. It results in a tendon loss or damage, due to too much pressure on the muscles in an area of the groin or thighs.

•    Rotator Cuff Tear: - It is one of the darkest fears of the pitchers, tennis players. The rotator cuff is the group of four tendons and muscles that converge around the shoulder joints and the upper arm bone. Too much stress can cause tears in the tendons or the bones.

•    Tennis Elbow: - Swelling or inflammation of the tendons, causing pain in the elbow or arm.

.Although minor injuries or skin lesions can be treated with simple remedies; severe cases need only surgical reconstruction of the affected area due to its poor healing. These options can encounter serious complications during the procedure and hence are in strong demand of alternative therapies. Advancells, situated at Noida is excited by the prodigious prospects of stem cells in treating various diseases; hence they are constantly updating our knowledge and technology to suit unique specifications of each patient. They are offering safe treatment pattern, by offering "Autologous stem cells from your own Bone Marrow/Adipose Tissue"

Platelet-Rich Plasma or PRP: How safe it is?

Platelet-Rich Plasma or PRP: How safe it is?

Platelet rich plasma (PRP) is a revolutionary no-operative treatment preference that not only relives pain but promotes long lasting healing of many diseases. This rapidly emerging technique shows very promising potential for many conditions such as arthritis, tendonitis, ligament sprains and tears, etc. PRP is not something that subsides over time as with a conventional pain injection.

As, our blood is made up of 93% red blood cells, 6% white blood cells, 1% platelets and plasma where platelets are best known for their function of blood-clotting to stop bleeding. Platelets, yet, are much more considerable than this, as human platelets are also a critical component in injury healing. The body’s first response to tissue injury is to transport platelets to the area. Platelets begin repair and attract Stem Cells to the injury. Injecting these growth factors into injured ligaments, tendons, and joints trigger the natural repair process. Objective of PRP is to maximize the number of platelets while minimizing the number of red blood cells in a solution that is injected into the injured or pained area(s). PRP is created in a simple, painless and conventional way. The entire process of drawing blood to solution preparation only takes approximately 25-30 minutes. 30 ml of blood is drawn from the patient, just like a routine blood test. Once the blood is drawn it is then placed into a centrifuge. The centrifuge is a machine that spins the blood at high speeds in order to separate the blood into red blood cells and concentrated platelets. Once the blood is estranged the red blood cells are discarded, and we are left with concentrated platelet rich plasma (PRP) which is ready to be used in the treatment process.

PRP treatment works most effectively for chronic ligament and tendon sprains/strains that have failed other conservative treatment. With any treatment option the outcome and sustained results are highly dependent on the extent of the injury. For example in the case of mild arthritis, PRP could potentially prevent the development of further degeneration. However, in advanced arthritic degeneration the goal of the treatment is to minimize pain and improve function. PRP (potentially if used in tandem with the use of stem cells) could avoid surgery such as joint replacements and potentially spinal fusion.

The advantage to PRP therapy is different from other treatments as it has a persistent outcome and is categorized as an everlasting fix. The period for experiencing results is dependent upon the area of injury and the extent of the injury. On average, most patients start to see signs of improvement in the form of reduced pain or increased function within four to six weeks.  Generally, PRP is an especially safe treatment option with no risk of allergic result because it is your own blood. However, whenever a needle is placed in the body, there is a risk of infection, bleeding, and nerve damage. These risks do not happen a lot, and are very rare. 

Liver Treatments with Stem Cells: “The powers” need power to make them powerful!

“Stop acting like a god in Greek mythology without any empathy for the human beings!”

Sounding weird? But for those who believe in mythology or has a strong interest in reading the myth can correlate the phrase with the Greek titan Prometheus, who was tortured by the hideous attempt of Greek God to punish him for exposing the secrets of gods to men! His liver was preyed by the eagles and his sufferings went eternal due to the liver’s ability to redevelop. Although eagles grew weary of the daily feast from a constantly replenished source; the legend tried to explain the world, the unexplainable………….the substratum of the “Power of Regeneration”.

As per the mythology,” There could not be any life without regeneration!” but the science says “There could not be any death with regeneration”

Let’s explore a science behind the enigma of regeneration! Regeneration in medicine, as has been tagged, typically involves achieving back the lost functions of various organs to address vast majority of medical problems. However scientists, who have commented on the history of the regenerative medicine, have also debated over the facts that organs most liable to be injured and therefore most likely in need of regenerative treatments are indeed those with the greatest regenerative capability. The Liver can be topped amongst this list.

Our liver is a phenomenal organ with an intrinsic capacity to regenerate after its loss either by accident or from injury. This tremendous regenerative potential of liver has been observed in number of rat models wherein after partial removal of the liver approximately 70% of the lost tissue is generated. The similar situation has also been observed in case of human beings where few years after the liver transplants, liver becomes hypertrophic i.e. gets bigger to compensate for the loss. If this is the case then questions might arise in your mind that how does liver regenerate on its own, and if it does, then why does it need an external dose of regenerative medicine?

The answer to this question lies in the fact that the tissues like liver have inherent sources of power inside them. These powers are entities which are ready for the action all the time. If given appropriate circumstances these powers can interact with the surrounding environment to stop further destruction and to enhance repairing of what has been damaged, as a routine practice! They are named as “Stem Cells”. 

Stem cells, with the capability to be any cells of the body can trigger reparative regeneration inside the liver to form lost hepatocytes. But in chronic conditions such as scarred liver tissue, liver injury etc, these cells have to do whole lot of work and hence become overburdened. This stressful situation provides the rationale for liver losing its ability to regenerate over the period of time with the complete functional damage.  But with the scientific advances it is possible to boost the process of liver regeneration externally.

Apart from liver there are some other habitats for residential stem cells such as Adipose Tissue, Bone Marrow which can be isolated outside the body. Thanks to the advances of the tissue culture techniques! The Technique is helping worldwide healthcare professionals to isolate stem cells outside the body, concentrate them in large number and reinsert back into the targeted site, where they can secrete number of growth factors, cytokines etc to start the process of healing.

Liver Treatment with Advancells

At Advancells, we are utilising your own stem cells isolated from the two abundant and potent sources such as Adipose Tissue and/or Bone Marrow as a treatment regimen for Liver Diseases. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.