Stem Cell Treatment For Male Infertility

Although the root cause of concern related to male infertility symptoms often remains a mystery, the research in regenerative medicine has displayed great potential in developing the treatment of infertility with stem cells by targeting the reasons for infertility. Today, 1 out of 8 couples in developed countries are facing issues in the treatment of male infertility. Moreover, about half of these issues are being attributed to semen abnormalities in the male partner. Earlier, things were not clear as to why penile erection fails to occur or what leads to reduced sperm mobility, etc. With extensive research, these challenges are now comprehensible to therapeutic ventures resulting in new treatments of male infertility using autologous transplant/allogeneic transplant for adipose-derived mesenchymal stromal cells treatment and bone marrow stromal cells treatment. This new insight on the treatment of male infertility has helped in identifying the potential to overcome infertility with stem cells, primarily using autologous stem cell transplant in form of hematopoietic stem cell transplant or read more

5 Astonishing facts on Amyotrophic Lateral Sclerosis (ALS)

 Amyotrophic lateral sclerosis, or ALS, causes damage to motor neurons, which regulate voluntary movement in your body. It is a progressive condition that leads to paralysis, respiratory failure, and death over time. ALS is also known as Lou Gehrig's disease that is named after a famous baseball player who died of the condition in the late 1930s. While there is currently no treatment for ALS, emerging discoveries are opening up new research opportunities for those who are affected. 

 Here are some interesting facts for you on ALS:

1.  Approximately 5 to 10% of ALS cases are inherited

About 95% of ALS are ‘sporadic’, meaning that the cause is unknown. Certain people are more vulnerable to ALS due to genetic abnormalities. The rest 5% are ‘familial’ which means the disease is passed down from generation to generation. Some genes are shared by the two types. If a parent has familial ALS, their child has a 50% risk of adopting the mutation and developing the disease. 

2. The symptoms of ALS don’t follow a specific pattern

If you have ALS, you might realize that you are dropping items more frequently, tripping, or stuttering your words at first, but the symptoms of ALS differ from person to person. Twitching, muscle spasms, stiffness in the arms and legs, excessive saliva, and outbursts of laughing or sobbing are some of the symptoms of ALS. Although the disease may appear to be slow-moving at first, ALS sufferers eventually acquire severe muscle weakness, become paralysed, and require aid breathing.

3. About 15% of ALS diagnoses are inaccurate

Because the symptoms of ALS are similar to those of other diseases and there is no specific test to confirm the diagnosis, it can take a year or more to receive a diagnosis. Consider seeking a second opinion if you or someone you know has been diagnosed with ALS. Men are affected by ALS at a younger age than women, but the gender gap narrows over time. People who have served in the military are twice as likely to get ALS for unexplained reasons.

4. Available treatments for ALS

Riluzole and Edaravone, two medicines, may decrease disease development and prolong life by a few months. Sudden outbursts of laughing or sobbing is a condition that affects some ALS patients and can be treated with medication. People with ALS are cared for by a neurologist, but physical and occupational therapists, respiratory therapists, nutritionists, and social workers or counsellors can assist patients to maintain function and independence for extended periods of time. There is currently no cure for ALS, however, there is extensive research into medications that may delay or stop the disease's course.

5. A period of no disease progression

It's not uncommon for people with ALS to have times where the disease stops developing for weeks or months for unspecified reasons. This is referred to as an "arrest." Some individuals can experience reversals, or improvements in function, in a few, rare situations. Sadly, these intervals rarely endure more than a few months until the symptoms recur and progression of ALS begins, though they can continue up to a year in exceptional circumstances.

What you should know about autism spectrum?

 Autism spectrum disorder is a brain development disorder that influences how a person thinks and mingles with others, causing difficulties with social interaction and communication. The disorder also features restricted and repetitive behavioural traits. The term "spectrum" refers to the vast variety of symptoms and intensity associated with an autism spectrum disorder. Autism spectrum disorder can be found in early childhood and later causes difficulties in functioning in society — for example, socially, in school, or at work. However, there are many therapies for the treatment of autism, for instance, speech therapy, behavioural therapies, etc. Stem cell therapy for the treatment of autism has emerged as a novel therapy and has revolutionized the field of regenerative medicine. Several studies have shown the wonders of stem cells for the treatment of autism and it is effective. Advancells is the leading organization that provides the best stem cell therapy for autism in India. With sophisticated technological assistance, scientific excellence, and a competent quality management system, Advancells is able to provide fully customised treatment solutions based on individualised needs.

Nutrition Can Improve Endometrial Thinning

 Endometrial thinning can be caused due to irregular periods or due to low estrogen levels. Such conditions can also show up due to eating disorders or autoimmune disorders in the body.

Can nutrition help?

A healthy uterine lining or endometrial thinning helps women in regular menstrual discharge and getting pregnant by ensuring successful implantation. Besides hormonal medications, a habit of exercising can increase the blood flow throughout your body and that includes blood flow to one’s uterus. A good amount of rest and meditation for de-stressing can also help in natural hormone regulation in the body. Further habits to avoid definitely include smoking and caffeine intake.

So, it is evident that a healthy lifestyle plays a huge role in maintaining endometrial thickness and thus Nutrition is an important factor. Many clinical studies significantly suggest that nutrition may have a relevant impact on endometrial thickness. Here are some nutritional strategies that can help:

• Vitamin E rich food

Vitamin E may assist thickening of the endometrium wall and foods like nuts, seeds, and avocados are rich in vitamin E. For a healthy woman, an amount of 7mg/day can be gained by proper diet but studies have used much higher concentrations, which are not always suitable for good health. Vitamin E supplements must be taken after consulting with one’s doctor as large doses of vitamin E during pregnancy have been known to cause ‘small for gestational age’ babies.

• L-arginine rich food

L-arginine is produced by our body and helps in protein building as an amino acid. This amino acid also works as a vasodilator and helps in blood flow. For having foods rich in L-arginine, one should look for a diet rich in are dairy products, soy, beans, fish, poultry products. Before taking supplements, one should look for proper medical advice.

• Omega-3 rich food

Omega-3 is a well-known factor that promotes hormonal regulation and increased the chances of embryo implantation in the uterus. Some common foods rich in omega-3 are avocados, fatty fish, spinach and walnuts.

• Whole grains

For a healthy female body, 48gm/day of whole grains are suggested but seldom people follow or get even close to that amount. Seedy bread, bran rice, and even popcorn are considered whole grains and these are rich in carbohydrates, proteins, fibers, B-vitamins, and antioxidants. Some studies have suggested that women who have higher whole grain intake have higher chances of implantation with IVF. Moreover, for every additional serve of whole grains per day, uterine lining can increase by an average of 0.4 mm. It might not sound much but it makes quite a difference!.

Best Stem Cell Therapy in India

 

What Are Stem Cells?

Stem cells are unspecialized cells of the body with the potential of self-renewal and differentiation. Our body starts with totipotent cells, growing up to three layers (endo, ecto, and mesoderm) having pluripotent stem cells. As an adult, the body has reserves of multipotent and unipotent stem cells.

Why Are Stem Cells Getting Attention?

• Increased understanding of diseases by studying stem cells and their maturation.
• Stem cells can be programmed to differentiate into specific cells for tissue-specific regeneration.
• Many patients with diabetes, Parkinson’s disease, ALS, Alzheimer’s disease, osteoarthritis, autism, etc. have seen improvements with stem cell therapy approaches.
• Stem cells have the potential to grow tissues for transplants in regenerative medicine.
• Drug safety testing research can use stem cells in 3D culture models.

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